Clenbuterol is a sympathomimetic drug used mainly in bronchodilator formulations for asthma and COPD sufferers. Through the action of adrenoreceptors known as beta-1 and beta-2, sympathomimetic drugs produce a physiological reaction that mimics sympathetic nervous system stimulation. Clenbuterol is a selective beta-2 agonist, showing no effect on beta-1 receptors. Thus, clenbuterol can effectively relieve chronic airway obstruction without triggering cardiovascular side effects that non-specific beta agonists might induce.
In the human body, clenbuterol was shown to have an extended half-life at about 34 hours, stabilizing blood levels more effectively. Because of this, dosing schedules become more manageable, often requiring only once or twice daily doses. Patients on clenbuterol medications are more compliant with the therapy because it is easy to follow. Clenbuterol formulations are not approved for use in the US, although comparable drugs are FDA-approved for asthma and COPD remedies. This omission may be partly due to profitability concerns in the crowded market for bronchodilators. Nevertheless, clenbuterol is easily available to US patients through overseas sources.
Clenbuterol has also been touted as a valuable ingredient of weight-loss supplements and you can Buy Steroids Canada With Canabolics. The thermogenic and anti-catabolic action of the drug can raise core temperatures of the human body, thus burning more calories. Studies have indicated that increasing core temperature by 1ºF will increase calorie burn by about 5 percent. Acting as a beta-agonist, clenbuterol can hasten the conversion of triglycerides into free fatty acids by stimulating the breakdown of fat cells. Body fat is lost while muscle mass is enhanced.
In the August 1995 issue of the Medicine and Science in Sports and Exercise journal, a clenbuterol review questioned its anabolic efficacy since claims were associated with animal data alone, in doses much higher than normally included in bronchodilators. Today, weight-loss experts insist that clenbuterol is effective in fat breakdown. Athletes, performers and weight-loss proponents back up these claims with their own testimonies.
Since clenbuterol is a stimulant, it has been incorrectly considered a regulated substance by professional athletic regulations. It is not a steroid but it stimulates the central nervous system so that athletes need to manage their doses and cycling to achieve optimum fat loss and muscle build-up. Clenbuterol is available as liquid, nasal spray or intravenous administration but tablets are the recommended dosing method.
Men may tolerate a daily dose of two to eight tablets while women will see results with two to four tablets. Ideal dosing can be determined by clenbuterol cycling where daily doses are gradually raised. This system will minimize side effects like insomnia, hypertension, nausea, and sweating and hand tremors. Side effects subside as the body tolerates the doses in about a week’s time. Clenbuterol users report some weight loss even without diet and rigorous exercise.